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Phase I and pharmacokinetic study of the oral farnesyl transferase inhibitor SCH 66336 given twice daily to patients with advanced solid tumors.

par Eskens, Ferry ALM;Awada, Ahmad ;Cutler, D L;de Jonge, M J;Luyten, G P;Faber, Marije;Statkevich, Paul;Sparreboom, A;Verweij, Jaap;Hanauske, Axel-R;Piccart-Gebhart, Martine ;European Organization for Research and Treatment of Cancer Early Clinical Studies Group,
Référence Journal of clinical oncology, 19, 4, page (1167-1175)
Publication Publié, 2001-02

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Titre:	Phase I and pharmacokinetic study of the oral farnesyl transferase inhibitor SCH 66336 given twice daily to patients with advanced solid tumors.
Auteur:	Eskens, Ferry ALM; Awada, Ahmad; Cutler, D L; de Jonge, M J; Luyten, G P; Faber, Marije; Statkevich, Paul; Sparreboom, A; Verweij, Jaap; Hanauske, Axel-R; Piccart-Gebhart, Martine; European Organization for Research and Treatment of Cancer Early Clinical Studies Group,
Informations sur la publication:	Journal of clinical oncology, 19, 4, page (1167-1175)
Statut de publication:	Publié, 2001-02
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	Administration, Oral
	Adult
	Aged
	Alkyl and Aryl Transferases -- antagonists & inhibitors
	Antineoplastic Agents -- administration & dosage
	Antineoplastic Agents -- pharmacokinetics
	Antineoplastic Agents -- therapeutic use
	Enzyme Inhibitors -- administration & dosage
	Enzyme Inhibitors -- pharmacokinetics
	Enzyme Inhibitors -- therapeutic use
	Farnesyltranstransferase
	Female
	Humans
	Male
	Middle Aged
	Piperidines -- pharmacokinetics
	Piperidines -- therapeutic use
	Pyridines -- pharmacokinetics
	Pyridines -- therapeutic use
Note générale:	Clinical Trial
	Clinical Trial, Phase I
	Journal Article
Langue:	Anglais
Identificateurs:	urn:issn:0732-183X
	info:pmid/11181683