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Prevention of pulmonary vascular remodeling and of decreased BMPR-2 expression by losartan therapy in shunt-induced pulmonary hypertension.

par Rondelet, Benoît ;Kerbaul, François;Van Beneden, Ronald ;Hubloue, Ives;Huez, Sandrine ;Fesler, P.;Remmelink, Myriam ;Brimioulle, Serge ;Salmon, Isabelle ;Naeije, Robert
Référence American journal of physiology. Heart and circulatory physiology, 289, 6, page (H2319-H2324)
Publication Publié, 2005-12

Article révisé par les pairs

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Titre:	Prevention of pulmonary vascular remodeling and of decreased BMPR-2 expression by losartan therapy in shunt-induced pulmonary hypertension.
Auteur:	Rondelet, Benoît; Kerbaul, François; Van Beneden, Ronald; Hubloue, Ives; Huez, Sandrine; Fesler, P.; Remmelink, Myriam; Brimioulle, Serge; Salmon, Isabelle; Naeije, Robert
Informations sur la publication:	American journal of physiology. Heart and circulatory physiology, 289, 6, page (H2319-H2324)
Statut de publication:	Publié, 2005-12
Sujet CREF:	Sciences bio-médicales et agricoles
Mots-clés:	Angiopoietin
	Angiotensin II
	Bone morphogenetic protein receptor-2
	Endothelin-1
	Left-to-right shunt
MeSH keywords:	Animals
	Antihypertensive Agents -- administration & dosage
	Arteriovenous Shunt, Surgical -- adverse effects
	Gene Expression Regulation -- drug effects
	Hypertension, Pulmonary -- drug therapy
	Hypertension, Pulmonary -- metabolism
	Losartan -- administration & dosage
	Lung -- blood supply
	Lung -- drug effects
	Lung -- metabolism
	Neovascularization, Pathologic -- etiology
	Neovascularization, Pathologic -- metabolism
	Neovascularization, Pathologic -- prevention & control
	Pulmonary Artery -- drug effects
	Pulmonary Artery -- metabolism
	Pulmonary Artery -- pathology
	Swine
	Treatment Outcome
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
Langue:	Anglais
Identificateurs:	urn:issn:0363-6135
	info:doi/10.1152/ajpheart.00518.2005
	info:pii/00518.2005
	info:scp/28144460799
	info:pmid/16024566