Titre:
  • A novel transport and delivery mechanism underpins the effectiveness of prolyl-m-sarcolysyl-p-fluorophenylalanine (PSF) in a human melanoma xenograft nude-mouse model.
Auteur:Dierickx, Karen M E; Morandini, R; Nguyen, Thi hien; Sales, Francois; Kauffmann, Jean-Michel; Ghanem, Ghanem Elias
Informations sur la publication:Pigment Cell & Melanoma Research, 21, 4, page (439-450)
Statut de publication:Publié, 2008-08
Sujet CREF:Sciences bio-médicales et agricoles
Mots-clés:Alkylating agents
Drug targeting and delivery
Human melanoma-bearing nude mice
Melphalan
PSF
Tumor-associated proteases
MeSH keywords:Animals
Antineoplastic Agents -- administration & dosage
Antineoplastic Agents -- pharmacokinetics
Antineoplastic Agents -- pharmacology
Dipeptides -- administration & dosage
Dipeptides -- pharmacokinetics
Dipeptides -- pharmacology
Drug Delivery Systems -- methods
Drug Stability
Humans
Melanoma -- drug therapy
Melanoma -- pathology
Melphalan -- pharmacology
Melphalan -- therapeutic use
Mice
Mice, Nude
Models, Biological
Treatment Outcome
Tumor Cells, Cultured
Xenograft Model Antitumor Assays
p-Fluorophenylalanine -- administration & dosage
p-Fluorophenylalanine -- analogs & derivatives
p-Fluorophenylalanine -- pharmacokinetics
p-Fluorophenylalanine -- pharmacology
Note générale:Journal Article
Research Support, Non-U.S. Gov't
Langue:Anglais
Identificateurs:urn:issn:1755-1471
info:doi/10.1111/j.1755-148X.2008.00471.x
info:pii/PCR471
info:scp/47249108628
info:pmid/18627526