Conditional and specific NF-kappaB blockade protects pancreatic beta cells from diabetogenic agents.
par Eldor, R;Yeffet, A;Baum, K;Doviner, V;Amar, D;Ben-Neriah, Y;Christofori, G;Peled, Amnon;Carel, J C;Boitard, C;Klein, T;Serup, P;Eizirik, Decio L. ;Melloul, D
Référence Proceedings of the National Academy of Sciences of the United States of America, 103, 13, page (5072-5077)
Publication Publié, 2006
Référence Proceedings of the National Academy of Sciences of the United States of America, 103, 13, page (5072-5077)
Publication Publié, 2006
Article révisé par les pairs
Titre: |
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Auteur: | Eldor, R; Yeffet, A; Baum, K; Doviner, V; Amar, D; Ben-Neriah, Y; Christofori, G; Peled, Amnon; Carel, J C; Boitard, C; Klein, T; Serup, P; Eizirik, Decio L.; Melloul, D |
Informations sur la publication: | Proceedings of the National Academy of Sciences of the United States of America, 103, 13, page (5072-5077) |
Statut de publication: | Publié, 2006 |
Sujet CREF: | Sciences bio-médicales et agricoles |
Mots-clés: | Apoptosis |
Cytokine | |
Diabetes transgenic mice | |
Insulin | |
MeSH keywords: | Active Transport, Cell Nucleus -- drug effects |
Animals | |
Apoptosis -- drug effects | |
Cytokines | |
DNA -- metabolism | |
Diabetes Mellitus, Experimental -- chemically induced | |
Diabetes Mellitus, Experimental -- genetics | |
Diabetes Mellitus, Experimental -- metabolism | |
Diabetes Mellitus, Experimental -- pathology | |
Doxycycline -- pharmacology | |
Drug Resistance -- drug effects | |
Gene Expression Regulation, Enzymologic | |
I-kappa B Kinase -- genetics | |
I-kappa B Kinase -- metabolism | |
Interferon-gamma -- pharmacology | |
Interleukin-1 -- pharmacology | |
Islets of Langerhans -- drug effects | |
Islets of Langerhans -- metabolism | |
Islets of Langerhans -- pathology | |
Lymphocytes -- cytology | |
Mice | |
Mice, Transgenic | |
Mutation -- genetics | |
NF-kappa B -- antagonists & inhibitors | |
NF-kappa B -- metabolism | |
Protein Binding | |
Streptozocin -- pharmacology | |
Tissue Culture Techniques | |
Note générale: | Journal Article |
Research Support, Non-U.S. Gov't | |
Langue: | Anglais |
Identificateurs: | urn:issn:0027-8424 |
info:doi/10.1073/pnas.0508166103 | |
info:pii/0508166103 | |
info:scp/33645518035 | |
info:pmid/16551748 | |
PMC1458796 |