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Is risk of central nervous system (CNS) relapse related to adjuvant taxane treatment in node-positive breast cancer? Results of the CNS substudy in the intergroup Phase III BIG 02-98 Trial.

par Pestalozzi, B C;Francis, P;Quinaux, E;Dolci, Stella;de Azambuja, Evandro ;Gelber, R D;Viale, G;Balil, A;Andersson, Michael;Nordenskjöld, B;Gnant, Michael;Gutierrez, J;Láng, I;Crown, J P A;Piccart-Gebhart, Martine ;BIG 02-98 Collaborative Group,
Référence Annals of oncology, 19, 11, page (1837-1841)
Publication Publié, 2008-11

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Titre:	Is risk of central nervous system (CNS) relapse related to adjuvant taxane treatment in node-positive breast cancer? Results of the CNS substudy in the intergroup Phase III BIG 02-98 Trial.
Auteur:	Pestalozzi, B C; Francis, P; Quinaux, E; Dolci, Stella; de Azambuja, Evandro; Gelber, R D; Viale, G; Balil, A; Andersson, Michael; Nordenskjöld, B; Gnant, Michael; Gutierrez, J; Láng, I; Crown, J P A; Piccart-Gebhart, Martine; BIG 02-98 Collaborative Group,
Informations sur la publication:	Annals of oncology, 19, 11, page (1837-1841)
Statut de publication:	Publié, 2008-11
Sujet CREF:	Sciences bio-médicales et agricoles
Mots-clés:	Adjuvant chemotherapy
	Breast cancer
	Central nervous system
	Meningeal carcinomatosis
	Taxane
	Trastuzumab
MeSH keywords:	Adolescent
	Adult
	Aged
	Antineoplastic Combined Chemotherapy Protocols -- therapeutic use
	Breast Neoplasms -- cerebrospinal fluid
	Breast Neoplasms -- drug therapy
	Breast Neoplasms -- pathology
	Central Nervous System Neoplasms -- cerebrospinal fluid
	Central Nervous System Neoplasms -- secondary
	Chemotherapy, Adjuvant
	Cyclophosphamide -- administration & dosage
	Doxorubicin -- administration & dosage
	Female
	Fluorouracil -- administration & dosage
	Humans
	Methotrexate -- administration & dosage
	Middle Aged
	Neoplasm Metastasis
	Taxoids -- administration & dosage
	Taxoids -- adverse effects
	Treatment Failure
Note générale:	Clinical Trial, Phase III
	Journal Article
	Randomized Controlled Trial
	Research Support, N.I.H., Extramural
	Research Support, Non-U.S. Gov't
Langue:	Anglais
Identificateurs:	urn:issn:0923-7534
	info:doi/10.1093/annonc/mdn385
	info:pii/mdn385
	info:scp/54949136570
	info:pmid/18562328
	PMC2733076