Article révisé par les pairs
Titre:
  • RF9, a potent and selective neuropeptide FF receptor antagonist, prevents opioid-induced tolerance associated with hyperalgesia.
Auteur:Simonin, Frédéric; Schmitt, M.; Laulin, Jean-Paul; Laboureyras, Emilie; Jhamandas, Jack H; MacTavish, David; Matifas, Audrey; Mollereau, Catherine; Laurent, Patrick; Parmentier, Marc; Kieffer, Brigitte L; Bourguignon, Jean-Jacques; Simonnet, Guy
Informations sur la publication:Proceedings of the National Academy of Sciences of the United States of America, 103, 2, page (466-471)
Statut de publication:Publié, 2006-01
Sujet CREF:Sciences bio-médicales et agricoles
Mots-clés:Analgesia
Antiopioid
Cardiac function
RFamide
MeSH keywords:Adamantane -- analogs & derivatives
Adamantane -- chemistry
Adamantane -- pharmacology
Amides -- chemistry
Analgesics, Opioid -- antagonists & inhibitors
Analgesics, Opioid -- pharmacology
Animals
Blood Pressure -- drug effects
COS Cells
Cercopithecus aethiops
Dipeptides -- chemistry
Dipeptides -- pharmacology
Drug Tolerance
Heart Rate -- drug effects
Heroin -- antagonists & inhibitors
Heroin -- pharmacology
Humans
Hyperalgesia -- chemically induced
Hyperalgesia -- metabolism
Hyperalgesia -- physiopathology
Ligands
Molecular Structure
Rats
Receptors, Neuropeptide -- antagonists & inhibitors
Receptors, Neuropeptide -- metabolism
Note générale:Journal Article
Research Support, Non-U.S. Gov't
Langue:Anglais
Identificateurs:urn:issn:0027-8424
info:doi/10.1073/pnas.0502090103
info:pii/0502090103
info:scp/31044431725
info:pmid/16407169
PMC1326150

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