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Evidence for the involvement of the adenosine A(2A) receptor in the lowered susceptibility to pentylenetetrazol-induced seizures produced in mice by long-term treatment with caffeine.

par El Yacoubi, Malika;Ledent, Catherine ;Parmentier, Marc ;Costentin, Jean;Vaugeois, Jean-Marie
Référence Neuropharmacology, 55, 1, page (35-40)
Publication Publié, 2008-07

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Titre:	Evidence for the involvement of the adenosine A(2A) receptor in the lowered susceptibility to pentylenetetrazol-induced seizures produced in mice by long-term treatment with caffeine.
Auteur:	El Yacoubi, Malika; Ledent, Catherine; Parmentier, Marc; Costentin, Jean; Vaugeois, Jean-Marie
Informations sur la publication:	Neuropharmacology, 55, 1, page (35-40)
Statut de publication:	Publié, 2008-07
Sujet CREF:	Sciences bio-médicales et agricoles
Mots-clés:	Adenosine A2A receptor
	Caffeine
	Kindling
	Knockout mice
	Pentylenetetrazol
	Seizure
MeSH keywords:	Analysis of Variance
	Animals
	Caffeine -- administration & dosage
	Disease Models, Animal
	Disease Susceptibility
	Dose-Response Relationship, Drug
	Male
	Mice
	Mice, Knockout
	Pentylenetetrazole
	Phosphodiesterase Inhibitors -- administration & dosage
	Reaction Time -- drug effects
	Reaction Time -- genetics
	Receptor, Adenosine A2A -- deficiency
	Receptor, Adenosine A2A -- physiology
	Seizures -- chemically induced
	Seizures -- drug therapy
	Time Factors
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
Langue:	Anglais
Identificateurs:	urn:issn:0028-3908
	info:doi/10.1016/j.neuropharm.2008.04.007
	info:pii/S0028-3908(08)00104-4
	info:scp/45649083940
	info:pmid/18486156