Micronuclei to detect in vivo chemotherapy damage in a p53 mutated solid tumour.

Driessens, Grégory; Harsan, L; Robaye, Bernard; Waroquier, Dominique; Browaeys, Patrick; Giannakopoulos, Xenofon; Velu, Thierry; Bruyns, C

doi:doi/10.1038/sj.bjc.6601163

Recherche avancée | Historique de recherche Mon DI-fusion | À propos de DI-fusion | Contact |

Citer

Micronuclei to detect in vivo chemotherapy damage in a p53 mutated solid tumour.

par Driessens, Grégory

;Harsan, L ;Robaye, Bernard

;Waroquier, Dominique

;Browaeys, Patrick

;Giannakopoulos, Xenofon ;Velu, Thierry

;Bruyns, C
Référence British Journal of Cancer, 89, 4, page (727-729)
Publication Publié, 2003-08

Article révisé par les pairs

Résumé :

Apoptosis induction and micronuclei formation were compared following cytotoxic treatments in two rat glioma differing in p53 integrity. In vitro, micronuclei emergence but not apoptosis was linked to the p53 mutated status. In vivo, micronuclei assays were more sensitive to evaluate DNA damage induced by chemotherapy in a p53-mutated solid tumour.

Documents en relation

DI-fusion

Clinical profile of patients with primary Sjögren's syndrome with non-identified antinuclear autoantibodies
par Parisis, Dorian , Sarrand, Julie , Cabrol, Xavier , Delporte, Christine , Soyfoo, Muhammad Shahnawaz
Publication 2024-04-30
Ionizing radiation responses appear incidental to desiccation responses in the bdelloid rotifer Adineta vaga
par Moris, Victoria , Bruneau, Lucie , Berthe, Jérémy , Heuskin, Anne-Catherine , Penninckx, Sébastien , Ritter, Sylvia , Weber, Uli , Durante, Marco , Danchin, Etienne E.G.J. , Hespeels, Boris , Doninck, Karine Van
Publication 2024-12
ASO Author Reflections: Histological Growth Patterns of Colorectal Peritoneal Metastases Significantly Affect Prognosis in Patients Presenting for Curative-Intent Cytoreductive Surgery.
par El Asmar, Antoine , Kamdem, Leonel , Khaled, Charif , Liberale, Gabriel
Publication 2024-03
Engineered Wnt7a ligands rescue blood–brain barrier and cognitive deficits in a COVID-19 mouse model
par Trevino, Troy , Fogel, Avital , Otkiran, Guliz , Niladhuri, Seshadri , Sanborn, Mark , Class, Jacob , Almousawi, Ali , Vanhollebeke, Benoît , Tai, Leon M , Rehman, Jalees , Richner, Justin M , Lutz, Sarah E
Publication 2024-02-01
pycofitness—Evaluating the fitness landscape of RNA and protein sequences
par Pucci, Fabrizio , Zerihun, Mehari B , Rooman, Marianne , Schug, Alexander
Publication 2024-02-01

Référencement	Visibilité	Pérennité	Facilité
Les publications encodées constituent la bibliographie académique de l'Université.	Les documents déposés sont indexés par les moteurs de recherche (Google Scholar,…).	Les documents déposés en open-access sont archivés au sein du réseau de préservation SAFE-PLN (www.safepln.org).	Les listes de publications sont compatibles avec le CV-ULB, le FNRS et accessibles sur le web.