Titre:
  • Serotonin 5-HT(2B) receptor loss of function mutation in a patient with fenfluramine-associated primary pulmonary hypertension.
Auteur:Blanpain, Cédric; Le Poul, Emmanuel; Parma, Jasmine; Knoop, Christiane; Detheux, Michel; Parmentier, Marc; Vassart, Gilbert; Abramowicz, Marc
Informations sur la publication:Cardiovascular Research, 60, 3, page (518-528)
Statut de publication:Publié, 2003-12
Sujet CREF:Sciences bio-médicales et agricoles
Mots-clés:G-proteins
Human
Pulmonary circulation
Receptors
Serotonin (5-HT)
MeSH keywords:Animals
Appetite Depressants -- adverse effects
CHO Cells
COS Cells
Calcium -- metabolism
Case-Control Studies
Cell Membrane -- metabolism
Cricetinae
DNA Mutational Analysis
Female
Fenfluramine -- adverse effects
Flow Cytometry
Humans
Hypertension, Pulmonary -- chemically induced
Hypertension, Pulmonary -- metabolism
Male
Receptor, Serotonin, 5-HT2B -- genetics
Receptor, Serotonin, 5-HT2B -- metabolism
Note générale:Journal Article
Research Support, Non-U.S. Gov't
Langue:Anglais
Identificateurs:urn:issn:0008-6363
info:doi/10.1016/j.cardiores.2003.09.015
info:pii/S000863630300631X
info:scp/0345059064
info:pmid/14659797