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Serotonin 5-HT(2B) receptor loss of function mutation in a patient with fenfluramine-associated primary pulmonary hypertension.

par Blanpain, Cédric ;Le Poul, Emmanuel;Parma, Jasmine ;Knoop, Christiane ;Detheux, Michel;Parmentier, Marc ;Vassart, Gilbert ;Abramowicz, Marc
Référence Cardiovascular Research, 60, 3, page (518-528)
Publication Publié, 2003-12

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Titre:	Serotonin 5-HT(2B) receptor loss of function mutation in a patient with fenfluramine-associated primary pulmonary hypertension.
Auteur:	Blanpain, Cédric; Le Poul, Emmanuel; Parma, Jasmine; Knoop, Christiane; Detheux, Michel; Parmentier, Marc; Vassart, Gilbert; Abramowicz, Marc
Informations sur la publication:	Cardiovascular Research, 60, 3, page (518-528)
Statut de publication:	Publié, 2003-12
Sujet CREF:	Sciences bio-médicales et agricoles
Mots-clés:	G-proteins
	Human
	Pulmonary circulation
	Receptors
	Serotonin (5-HT)
MeSH keywords:	Animals
	Appetite Depressants -- adverse effects
	CHO Cells
	COS Cells
	Calcium -- metabolism
	Case-Control Studies
	Cell Membrane -- metabolism
	Cricetinae
	DNA Mutational Analysis
	Female
	Fenfluramine -- adverse effects
	Flow Cytometry
	Humans
	Hypertension, Pulmonary -- chemically induced
	Hypertension, Pulmonary -- metabolism
	Male
	Receptor, Serotonin, 5-HT2B -- genetics
	Receptor, Serotonin, 5-HT2B -- metabolism
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
Langue:	Anglais
Identificateurs:	urn:issn:0008-6363
	info:doi/10.1016/j.cardiores.2003.09.015
	info:pii/S000863630300631X
	info:scp/0345059064
	info:pmid/14659797