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The core domain of chemokines binds CCR5 extracellular domains while their amino terminus interacts with the transmembrane helix bundle.

par Blanpain, Cédric ;Doranz, Benjamin J.;Bondue, Antoine ;Govaerts, Cédric ;De Leener, Anne ;Vassart, Gilbert ;Doms, Robert W.;Proudfoot, Amanda;Parmentier, Marc
Référence The Journal of biological chemistry, 278, 7, page (5179-5187)
Publication Publié, 2003-02

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Titre:	The core domain of chemokines binds CCR5 extracellular domains while their amino terminus interacts with the transmembrane helix bundle.
Auteur:	Blanpain, Cédric; Doranz, Benjamin J.; Bondue, Antoine; Govaerts, Cédric; De Leener, Anne; Vassart, Gilbert; Doms, Robert W.; Proudfoot, Amanda; Parmentier, Marc
Informations sur la publication:	The Journal of biological chemistry, 278, 7, page (5179-5187)
Statut de publication:	Publié, 2003-02
Sujet CREF:	Sciences bio-médicales et agricoles
	Biochimie
	Biologie
	Biologie cellulaire
	Biologie moléculaire
	Biophysique
	Sciences biomédicales
MeSH keywords:	Amino Acid Motifs
	Amino Acid Sequence
	Animals
	Binding Sites
	CHO Cells
	Cell Membrane -- chemistry
	Cell Membrane -- metabolism
	Chemokine CCL3
	Chemokine CCL4
	Chemokine CCL5 -- chemistry
	Chemokine CCL5 -- metabolism
	Cricetinae
	Humans
	Macrophage Inflammatory Proteins -- chemistry
	Macrophage Inflammatory Proteins -- metabolism
	Molecular Sequence Data
	Mutation
	Protein Binding
	Protein Structure, Tertiary -- genetics
	Receptors, CCR5 -- chemistry
	Receptors, CCR5 -- genetics
	Receptors, CCR5 -- metabolism
	Signal Transduction
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
Langue:	Anglais
Identificateurs:	urn:issn:0021-9258
	info:doi/10.1074/jbc.M205684200
	info:pii/M205684200
	info:scp/0037799237
	info:pmid/12466283