Titre:
  • The core domain of chemokines binds CCR5 extracellular domains while their amino terminus interacts with the transmembrane helix bundle.
Auteur:Blanpain, Cédric; Doranz, Benjamin J.; Bondue, Antoine; Govaerts, Cédric; De Leener, Anne; Vassart, Gilbert; Doms, Robert W.; Proudfoot, Amanda; Parmentier, Marc
Informations sur la publication:The Journal of biological chemistry, 278, 7, page (5179-5187)
Statut de publication:Publié, 2003-02
Sujet CREF:Sciences bio-médicales et agricoles
Biochimie
Biologie
Biologie cellulaire
Biologie moléculaire
Biophysique
Sciences biomédicales
MeSH keywords:Amino Acid Motifs
Amino Acid Sequence
Animals
Binding Sites
CHO Cells
Cell Membrane -- chemistry
Cell Membrane -- metabolism
Chemokine CCL3
Chemokine CCL4
Chemokine CCL5 -- chemistry
Chemokine CCL5 -- metabolism
Cricetinae
Humans
Macrophage Inflammatory Proteins -- chemistry
Macrophage Inflammatory Proteins -- metabolism
Molecular Sequence Data
Mutation
Protein Binding
Protein Structure, Tertiary -- genetics
Receptors, CCR5 -- chemistry
Receptors, CCR5 -- genetics
Receptors, CCR5 -- metabolism
Signal Transduction
Note générale:Journal Article
Research Support, Non-U.S. Gov't
Langue:Anglais
Identificateurs:urn:issn:0021-9258
info:doi/10.1074/jbc.M205684200
info:pii/M205684200
info:scp/0037799237
info:pmid/12466283