Titre:
  • Two basic residues of the h-VPAC1 receptor second transmembrane helix are essential for ligand binding and signal transduction.
Auteur:Solano Haro, Rosa; Langer, Ingrid; Perret, Jason; Vertongen, Pascale; Juarranz Moratilla, Maria Guillerma; Robberecht, Patrick; Waelbroeck, Magali
Informations sur la publication:The Journal of biological chemistry, 276, 2, page (1084-1088)
Statut de publication:Publié, 2001-01
Sujet CREF:Sciences bio-médicales et agricoles
MeSH keywords:Adenylate Cyclase -- metabolism
Amino Acid Substitution
Animals
CHO Cells
Cell Membrane -- physiology
Cricetinae
Humans
Kinetics
Lysine
Mutagenesis, Site-Directed
Protein Structure, Secondary
Receptors, Vasoactive Intestinal Peptide -- chemistry
Receptors, Vasoactive Intestinal Peptide -- genetics
Receptors, Vasoactive Intestinal Peptide -- physiology
Receptors, Vasoactive Intestinal Polypeptide, Type I
Recombinant Proteins -- chemistry
Recombinant Proteins -- drug effects
Recombinant Proteins -- metabolism
Signal Transduction -- physiology
Transfection
Vasoactive Intestinal Peptide -- analogs & derivatives
Vasoactive Intestinal Peptide -- metabolism
Vasoactive Intestinal Peptide -- pharmacology
Note générale:Journal Article
Research Support, Non-U.S. Gov't
Langue:Anglais
Identificateurs:urn:issn:0021-9258
info:doi/10.1074/jbc.M007696200
info:pii/M007696200
info:pmid/11013258