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Synthesis and in vitro antitumor activity of novel ring D analogues of the marine pyridoacridine ascididemin: structure-activity relationship.

par Delfourne, Evelyne;Darro, Francis;Portefaix, Philippe;Galaup, Chantal;Bayssade, Sylvie;Bouteillé, Anne;Le Corre, Laurent;Bastide, Jean;Collignon, Françoise;Lesur, Brigitte;Frydman, Armand;Kiss, Robert
Référence Journal of medicinal chemistry, 45, 17, page (3765-3771)
Publication Publié, 2002-08

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Titre:	Synthesis and in vitro antitumor activity of novel ring D analogues of the marine pyridoacridine ascididemin: structure-activity relationship.
Auteur:	Delfourne, Evelyne; Darro, Francis; Portefaix, Philippe; Galaup, Chantal; Bayssade, Sylvie; Bouteillé, Anne; Le Corre, Laurent; Bastide, Jean; Collignon, Françoise; Lesur, Brigitte; Frydman, Armand; Kiss, Robert
Informations sur la publication:	Journal of medicinal chemistry, 45, 17, page (3765-3771)
Statut de publication:	Publié, 2002-08
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	Acridines -- chemical synthesis
	Acridines -- pharmacology
	Acridines -- toxicity
	Alkaloids -- chemical synthesis
	Alkaloids -- pharmacology
	Alkaloids -- toxicity
	Animals
	Antineoplastic Agents -- chemical synthesis
	Antineoplastic Agents -- pharmacology
	Antineoplastic Agents -- toxicity
	Cell Division -- drug effects
	Drug Screening Assays, Antitumor
	Humans
	Inhibitory Concentration 50
	Mice
	Phenanthrolines
	Quinolines
	Structure-Activity Relationship
	Tumor Cells, Cultured
Note générale:	Journal Article
	SCOPUS: ar.j
Langue:	Anglais
Identificateurs:	urn:issn:0022-2623
	info:doi/10.1021/jm0208774
	info:pii/jm0208774
	info:scp/0037103341
	info:pmid/12166949