Titre:
  • Restoration of SHIP-1 activity in human leukemic cells modifies NF-kappaB activation pathway and cellular survival upon oxidative stress.
Auteur:Gloire, Geoffrey; Charlier, E; Rahmouni, Souad; Volanti, C; Chariot, Alain; Erneux, Christophe; Piette, Jacques
Informations sur la publication:Oncogene, 25, 40, page (5485-5494)
Statut de publication:Publié, 2006-09
Sujet CREF:Sciences bio-médicales et agricoles
Mots-clés:Apoptosis
IKK
Leukemic cells
NF-κB
Oxidative stress
SHIP-1
MeSH keywords:Apoptosis -- drug effects
Blotting, Western
Cell Survival -- drug effects
Flow Cytometry
Genetic Complementation Test
Humans
Hydrogen Peroxide -- pharmacology
I-kappa B Kinase -- metabolism
I-kappa B Proteins -- metabolism
Jurkat Cells
NF-kappa B -- metabolism
Oxidation-Reduction
Oxidative Stress
Phosphoric Monoester Hydrolases -- genetics
Phosphoric Monoester Hydrolases -- metabolism
Phosphorylation
Reactive Oxygen Species -- metabolism
Signal Transduction
Tumor Necrosis Factor-alpha -- pharmacology
Vanadates -- pharmacology
Note générale:Journal Article
Research Support, Non-U.S. Gov't
Langue:Anglais
Identificateurs:urn:issn:0950-9232
info:doi/10.1038/sj.onc.1209542
info:pii/1209542
info:scp/33748433789
info:pmid/16619039