Titre:
  • Galectin-1 knockdown increases sensitivity to temozolomide in a B16F10 mouse metastatic melanoma model.
Auteur:Mathieu, Véronique; Le Mercier, Marie; De Nève, Nancy; Sauvage, Sébastien; Gras, Thierry; Roland, Isabelle; Lefranc, Florence; Kiss, Robert
Informations sur la publication:Journal of investigative dermatology, 127, 10, page (2399-2410)
Statut de publication:Publié, 2007-10
Sujet CREF:Sciences bio-médicales et agricoles
MeSH keywords:Animals
Antineoplastic Agents -- therapeutic use
Antineoplastic Agents, Alkylating -- pharmacology
Antineoplastic Agents, Alkylating -- therapeutic use
Apoptosis -- drug effects
Cathepsin B -- metabolism
Cell Line, Tumor
Cisplatin -- therapeutic use
Dacarbazine -- analogs & derivatives
Dacarbazine -- pharmacology
Dacarbazine -- therapeutic use
Disease Models, Animal
Female
Galectin 1 -- genetics
Galectin 1 -- physiology
Gene Expression Regulation, Neoplastic -- drug effects
Gene Expression Regulation, Neoplastic -- physiology
HSP72 Heat-Shock Proteins -- physiology
Melanoma -- drug therapy
Melanoma -- pathology
Melanoma -- physiopathology
Mice
Mice, Knockout
RNA, Small Interfering -- pharmacology
Skin Neoplasms -- drug therapy
Skin Neoplasms -- pathology
Skin Neoplasms -- physiopathology
Xenograft Model Antitumor Assays
Note générale:Comparative Study
Journal Article
Research Support, Non-U.S. Gov't
Langue:Anglais
Identificateurs:urn:issn:0022-202X
info:doi/10.1038/sj.jid.5700869
info:pii/5700869
info:scp/34848896271
info:pmid/17495956