Titre:
  • Altered neuron excitability and synaptic plasticity in the cerebellar granular layer of juvenile prion protein knock-out mice with impaired motor control.
Auteur:Prestori, F.; Rossi, Pier Luca; Bearzatto, Bertrand; Laine, J.; Diwakar, S.; Necchi, D.
Informations sur la publication:The Journal of neuroscience, 28, 28, page (7091-7103)
Statut de publication:Publié, 2008-07
Sujet CREF:Sciences bio-médicales et agricoles
Mots-clés:Action potential
Cerebellum
Granule cell
LTP
Motor control
Prion
MeSH keywords:Age Factors
Animals
Animals, Newborn
Bromodeoxyuridine -- metabolism
Cell Proliferation
Cerebellum -- pathology
Dose-Response Relationship, Radiation
Electric Stimulation -- methods
Excitatory Postsynaptic Potentials -- drug effects
Excitatory Postsynaptic Potentials -- physiology
Excitatory Postsynaptic Potentials -- radiation effects
Membrane Potentials -- drug effects
Membrane Potentials -- physiology
Mice
Mice, Inbred C57BL
Mice, Knockout
Microscopy, Electron, Transmission -- methods
Movement -- physiology
Movement Disorders -- genetics
Movement Disorders -- pathology
Movement Disorders -- physiopathology
Neural Pathways -- physiology
Neuronal Plasticity -- genetics
Neurons -- physiology
Neurons -- ultrastructure
Patch-Clamp Techniques -- methods
Prions -- genetics
Prions -- metabolism
Note générale:Journal Article
Research Support, Non-U.S. Gov't
Langue:Anglais
Identificateurs:urn:issn:0270-6474
info:doi/10.1523/JNEUROSCI.0409-08.2008
info:pii/28/28/7091
info:scp/49049112271
info:pmid/18614678