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Trypanosomiasis-induced B cell apoptosis results in loss of protective anti-parasite antibody responses and abolishment of vaccine-induced memory responses.

par Radwanska, Magdalena ;Guirnalda, Patrick;De Trez, Carl ;Ryffel, Bernard;Black, Samuel;Magez, Stefan
Référence PLoS pathogens, 4, 5, page (e1000078)
Publication Publié, 2008-05

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Titre:	Trypanosomiasis-induced B cell apoptosis results in loss of protective anti-parasite antibody responses and abolishment of vaccine-induced memory responses.
Auteur:	Radwanska, Magdalena; Guirnalda, Patrick; De Trez, Carl; Ryffel, Bernard; Black, Samuel; Magez, Stefan
Informations sur la publication:	PLoS pathogens, 4, 5, page (e1000078)
Statut de publication:	Publié, 2008-05
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	Animals
	Animals, Newborn
	Antibodies, Protozoan -- biosynthesis
	Apoptosis
	B-Lymphocytes -- pathology
	Cell Proliferation
	Dendritic Cells -- immunology
	Dendritic Cells -- parasitology
	Disease Models, Animal
	Flow Cytometry
	Gene Expression
	Host-Parasite Interactions
	Immunologic Memory -- immunology
	Immunophenotyping
	Mice
	Mice, Inbred BALB C
	RNA, Messenger -- metabolism
	Spleen -- immunology
	Spleen -- pathology
	Trypanosoma brucei brucei -- immunology
	Trypanosoma brucei brucei -- pathogenicity
	Trypanosomiasis, African -- immunology
	Vaccines -- administration & dosage
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
	SCOPUS: ar.j
Langue:	Anglais
Identificateurs:	urn:issn:1553-7374
	info:doi/10.1371/journal.ppat.1000078
	info:scp/44949219210
	info:pmid/18516300
	PMC2386555