Titre:
  • Kit K641E oncogene up-regulates Sprouty homolog 4 and trophoblast glycoprotein in interstitial cells of Cajal in a murine model of gastrointestinal stromal tumours.
Auteur:Gromova, Petra; Ralea, Sébastian; Lefort, Anne; Libert, Frédérick; Rubin, Brian P; Erneux, Christophe; Vanderwinden, Jean-Marie
Informations sur la publication:Journal of Cellular and Molecular Medicine, 13, 8A, page (1536-1548)
Statut de publication:Publié, 2009-08
Sujet CREF:Sciences bio-médicales et agricoles
Mots-clés:Gastrointestinal stromal tumour
In vivo model
Interstitial cells of Cajal
KIT
Receptor tyrosine kinase
MeSH keywords:Amino Acid Substitution -- genetics
Animals
Disease Models, Animal
Gastrointestinal Stromal Tumors -- enzymology
Gastrointestinal Stromal Tumors -- genetics
Gene Expression Profiling
Gene Expression Regulation, Neoplastic
Humans
Interstitial Cells of Cajal -- enzymology
Interstitial Cells of Cajal -- pathology
Membrane Glycoproteins -- genetics
Membrane Glycoproteins -- metabolism
Mice
Mutation -- genetics
Neoplasm Proteins -- genetics
Neoplasm Proteins -- metabolism
Nerve Tissue Proteins -- genetics
Nerve Tissue Proteins -- metabolism
Oligonucleotide Array Sequence Analysis
Proto-Oncogene Proteins c-kit -- genetics
Proto-Oncogene Proteins c-kit -- metabolism
Reproducibility of Results
Reverse Transcriptase Polymerase Chain Reaction
Up-Regulation -- genetics
Note générale:Journal Article
Research Support, Non-U.S. Gov't
Langue:Anglais
Identificateurs:urn:issn:1582-1838
info:doi/10.1111/j.1582-4934.2009.00768.x
info:pii/JCMM768
info:scp/70349332896
info:pmid/19453770