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Neuroprotective effect of zVAD against the neurotoxin 3-nitropropionic acid involves inhibition of calpain.

par Bizat, Nicolas;Galas, Marie-Christine ;Jacquard, Carine;Boyer, Frédéric;Hermel, Jean-Michel;Schiffmann, Serge N. ;Hantraye, Philippe;Blum, David ;Brouillet, Emmanuel
Référence Neuropharmacology, 49, 5, page (695-702)
Publication Publié, 2005-10

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Titre:	Neuroprotective effect of zVAD against the neurotoxin 3-nitropropionic acid involves inhibition of calpain.
Auteur:	Bizat, Nicolas; Galas, Marie-Christine; Jacquard, Carine; Boyer, Frédéric; Hermel, Jean-Michel; Schiffmann, Serge N.; Hantraye, Philippe; Blum, David; Brouillet, Emmanuel
Informations sur la publication:	Neuropharmacology, 49, 5, page (695-702)
Statut de publication:	Publié, 2005-10
Sujet CREF:	Sciences bio-médicales et agricoles
Mots-clés:	Calpain
	Calpain inhibitor
	Caspase
	Mitochondrial complex II inhibitor
	Neurodegeneration
	Neuroprotection
	Succinate dehydrogenase
MeSH keywords:	Animals
	Calpain -- antagonists & inhibitors
	Calpain -- metabolism
	Carrier Proteins -- metabolism
	Cell Death -- drug effects
	Huntington Disease -- pathology
	Immunohistochemistry
	Injections, Intraventricular
	Male
	Microfilament Proteins -- metabolism
	Neostriatum -- cytology
	Neostriatum -- drug effects
	Nerve Degeneration -- pathology
	Neuroprotective Agents -- administration & dosage
	Neuroprotective Agents -- pharmacology
	Nitro Compounds
	Oligopeptides -- administration & dosage
	Oligopeptides -- pharmacology
	Propionic Acids -- antagonists & inhibitors
	Propionic Acids -- toxicity
	Protease Inhibitors
	Rats
	Rats, Inbred Lew
	Rats, Wistar
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
Langue:	Anglais
Identificateurs:	urn:issn:0028-3908
	info:doi/10.1016/j.neuropharm.2005.04.030
	info:pii/S0028-3908(05)00184-X
	info:scp/23944475829
	info:pmid/15998526