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The adenosine A1 receptor agonist adenosine amine congener exerts a neuroprotective effect against the development of striatal lesions and motor impairments in the 3-nitropropionic acid model of neurotoxicity.

par Blum, David ;Gall, David ;Galas, Marie-Christine ;D'Alcantara, Pablo ;Bantubungi, Kadiombo ;Schiffmann, Serge N.
Référence The Journal of neuroscience, 22, 20, page (9122-9133)
Publication Publié, 2002-10

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Titre:	The adenosine A1 receptor agonist adenosine amine congener exerts a neuroprotective effect against the development of striatal lesions and motor impairments in the 3-nitropropionic acid model of neurotoxicity.
Auteur:	Blum, David; Gall, David; Galas, Marie-Christine; D'Alcantara, Pablo; Bantubungi, Kadiombo; Schiffmann, Serge N.
Informations sur la publication:	The Journal of neuroscience, 22, 20, page (9122-9133)
Statut de publication:	Publié, 2002-10
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	Adenosine -- analogs & derivatives
	Adenosine -- pharmacology
	Animals
	Behavior, Animal -- drug effects
	Binding, Competitive -- drug effects
	Body Weight -- drug effects
	Cerebral Cortex -- drug effects
	Cerebral Cortex -- pathology
	Corpus Striatum -- drug effects
	Corpus Striatum -- pathology
	Disease Models, Animal
	Dystonia -- etiology
	Dystonia -- physiopathology
	Dystonia -- prevention & control
	Enkephalins -- biosynthesis
	Enkephalins -- genetics
	Hindlimb -- physiopathology
	Huntington Disease -- chemically induced
	Huntington Disease -- pathology
	Huntington Disease -- physiopathology
	Huntington Disease -- prevention & control
	Male
	Mitochondria -- drug effects
	Motor Activity -- drug effects
	Neuroprotective Agents -- pharmacology
	Neurotoxins
	Nitro Compounds
	Propionic Acids
	RNA, Messenger -- biosynthesis
	Rats
	Rats, Inbred Lew
	Receptors, Purinergic P1 -- agonists
	Reproducibility of Results
	Succinate Dehydrogenase -- antagonists & inhibitors
	Succinate Dehydrogenase -- metabolism
	Synaptic Transmission -- drug effects
	Treatment Outcome
Note générale:	In Vitro
	Journal Article
	Research Support, Non-U.S. Gov't
Langue:	Anglais
Identificateurs:	urn:issn:0270-6474
	info:pii/22/20/9122
	info:scp/0037107346
	info:pmid/12388620
	VX-002054