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Exogenous Nef protein activates NF-kappa B, AP-1, and c-Jun N-terminal kinase and stimulates HIV transcription in promonocytic cells. Role in AIDS pathogenesis.

par Varin, Audrey;Manna, Sunil K;Quivy, Vincent ;Decrion, Anne-Zélie;Van Lint, Carine ;Herbein, Georges;Aggarwal, Bharat B
Référence The Journal of biological chemistry, 278, 4, page (2219-2227)
Publication Publié, 2003

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Titre:	Exogenous Nef protein activates NF-kappa B, AP-1, and c-Jun N-terminal kinase and stimulates HIV transcription in promonocytic cells. Role in AIDS pathogenesis.
Auteur:	Varin, Audrey; Manna, Sunil K; Quivy, Vincent; Decrion, Anne-Zélie; Van Lint, Carine; Herbein, Georges; Aggarwal, Bharat B
Informations sur la publication:	The Journal of biological chemistry, 278, 4, page (2219-2227)
Statut de publication:	Publié, 2003
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	Acquired Immunodeficiency Syndrome -- virology
	Blotting, Western
	Cell Line
	Dose-Response Relationship, Drug
	Enzyme Activation
	Gene Products, nef -- physiology
	Genes, Reporter
	HIV -- metabolism
	Humans
	JNK Mitogen-Activated Protein Kinases
	Mitogen-Activated Protein Kinases -- metabolism
	Monocytes -- enzymology
	Monocytes -- virology
	NF-kappa B -- metabolism
	Signal Transduction
	Simian immunodeficiency virus -- metabolism
	Time Factors
	Transcription Factor AP-1 -- metabolism
	U937 Cells
	Virus Replication -- genetics
	nef Gene Products, Human Immunodeficiency Virus
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
	SCOPUS: ar.j
Langue:	Anglais
Identificateurs:	urn:issn:0021-9258
	info:doi/10.1074/jbc.M209622200
	info:pii/M209622200
	info:scp/0037462825
	info:pmid/12419805