• The neuropeptide pituitary adenylate cyclase activating polypeptide modulates Ca2+ and pro-inflammatory functions in human monocytes through the G protein-coupled receptors VPAC-1 and formyl peptide receptor-like 1.
Auteur:El Zein, Nabil; Badran, Bassam; Sariban, Eric
Informations sur la publication:Cell calcium, 43, 3, page (270-284)
Statut de publication:Publié, 2008-03
Sujet CREF:Sciences bio-médicales et agricoles
MeSH keywords:1-Phosphatidylinositol 3-Kinase -- metabolism
Antigens, CD11b -- metabolism
Calcium -- metabolism
Calcium Signaling -- drug effects
Enzyme Activation -- drug effects
Extracellular Space -- drug effects
Extracellular Space -- metabolism
GTP-Binding Protein alpha Subunits, Gi-Go -- metabolism
GTP-Binding Protein alpha Subunits, Gs -- metabolism
Inflammation -- metabolism
Intracellular Space -- drug effects
Intracellular Space -- metabolism
Mitogen-Activated Protein Kinases -- metabolism
Monocytes -- drug effects
Monocytes -- enzymology
Monocytes -- metabolism
NF-kappa B -- metabolism
Phosphorylation -- drug effects
Pituitary Adenylate Cyclase-Activating Polypeptide -- pharmacology
Protein Binding -- drug effects
Proto-Oncogene Proteins c-akt -- metabolism
Receptors, Formyl Peptide -- metabolism
Receptors, Lipoxin -- metabolism
Receptors, Vasoactive Intestinal Polypeptide, Type I -- metabolism
Respiratory Burst -- drug effects
Note générale:Journal Article
Research Support, Non-U.S. Gov't
SCOPUS: ar.j