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Gene expression profiling in frataxin deficient mice: microarray evidence for significant expression changes without detectable neurodegeneration.

par Coppola, Giovanni;Choi, Sang-Hyun;Santos, M M;Miranda, C;Tentler, Dmitri;Wexler, Eric M;Pandolfo, Massimo ;Geschwind, Daniel H
Référence Neurobiology of disease, 22, 2, page (302-311)
Publication Publié, 2006-05

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Titre:	Gene expression profiling in frataxin deficient mice: microarray evidence for significant expression changes without detectable neurodegeneration.
Auteur:	Coppola, Giovanni; Choi, Sang-Hyun; Santos, M M; Miranda, C; Tentler, Dmitri; Wexler, Eric M; Pandolfo, Massimo; Geschwind, Daniel H
Informations sur la publication:	Neurobiology of disease, 22, 2, page (302-311)
Statut de publication:	Publié, 2006-05
Sujet CREF:	Sciences bio-médicales et agricoles
Mots-clés:	Frataxin
	Friedreich's ataxia
	Knockin/knockout
	Microarray
	Mouse model
	Neurodegeneration
MeSH keywords:	Animals
	Cell Line
	Central Nervous System -- metabolism
	Central Nervous System -- pathology
	Central Nervous System -- physiopathology
	Disease Models, Animal
	Female
	Friedreich Ataxia -- genetics
	Friedreich Ataxia -- metabolism
	Friedreich Ataxia -- physiopathology
	Gene Expression Profiling
	Gene Expression Regulation -- genetics
	Genetic Predisposition to Disease -- genetics
	Humans
	Iron-Binding Proteins -- genetics
	Male
	Mice
	Mice, Knockout
	Mitochondria -- genetics
	Mitochondria -- metabolism
	Mutation -- genetics
	Nerve Degeneration -- genetics
	Nerve Degeneration -- metabolism
	Nerve Degeneration -- physiopathology
	Oligonucleotide Array Sequence Analysis
	Phenotype
	Spinal Cord -- metabolism
	Spinal Cord -- pathology
	Spinal Cord -- physiopathology
Note générale:	Journal Article
	Research Support, N.I.H., Extramural
	Research Support, Non-U.S. Gov't
Langue:	Anglais
Identificateurs:	urn:issn:0969-9961
	info:doi/10.1016/j.nbd.2005.11.014
	info:pii/S0969-9961(05)00313-X
	info:scp/33646162871
	info:pmid/16442805