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GGA*TCC-interrupted triplets in long GAA*TTC repeats inhibit the formation of triplex and sticky DNA structures, alleviate transcription inhibition, and reduce genetic instabilities.

par Sakamoto, N;Larson, J E;Iyer, R R;Montermini, L;Pandolfo, Massimo ;Wells, R D
Référence The Journal of biological chemistry, 276, 29, page (27178-27187)
Publication Publié, 2001-07

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Titre:	GGA*TCC-interrupted triplets in long GAA*TTC repeats inhibit the formation of triplex and sticky DNA structures, alleviate transcription inhibition, and reduce genetic instabilities.
Auteur:	Sakamoto, N; Larson, J E; Iyer, R R; Montermini, L; Pandolfo, Massimo; Wells, R D
Informations sur la publication:	The Journal of biological chemistry, 276, 29, page (27178-27187)
Statut de publication:	Publié, 2001-07
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	Base Sequence
	DNA -- chemistry
	DNA Primers
	Friedreich Ataxia -- genetics
	Mutagenesis, Site-Directed
	Nerve Tissue Proteins -- genetics
	Nucleic Acid Conformation
	Transcription, Genetic
	Trinucleotide Repeats
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
	Research Support, U.S. Gov't, P.H.S.
Langue:	Anglais
Identificateurs:	urn:issn:0021-9258
	info:doi/10.1074/jbc.M101852200
	info:pii/M101852200
	info:pmid/11325966