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The cytokine interleukin-1beta reduces the docking and fusion of insulin granules in pancreatic beta-cells, preferentially decreasing the first phase of exocytosis.

par Ohara-Imaizumi, M.;Cardozo, Alessandra K ;Kikuta, T.;Eizirik, Decio L. ;Nagamatsu, S.
Référence The Journal of biological chemistry, 279, 40, page (41271-41274)
Publication Publié, 2004

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Titre:	The cytokine interleukin-1beta reduces the docking and fusion of insulin granules in pancreatic beta-cells, preferentially decreasing the first phase of exocytosis.
Auteur:	Ohara-Imaizumi, M.; Cardozo, Alessandra K; Kikuta, T.; Eizirik, Decio L.; Nagamatsu, S.
Informations sur la publication:	The Journal of biological chemistry, 279, 40, page (41271-41274)
Statut de publication:	Publié, 2004
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	Animals
	Cells, Cultured
	Cytokines -- pharmacology
	Exocytosis -- drug effects
	Insulin -- metabolism
	Interleukin-1 -- pharmacology
	Islets of Langerhans -- metabolism
	Male
	Membrane Fusion -- drug effects
	Membrane Proteins -- analysis
	Membrane Proteins -- genetics
	Microscopy, Interference
	Nerve Tissue Proteins -- analysis
	Nerve Tissue Proteins -- genetics
	RNA, Messenger -- biosynthesis
	Rats
	Rats, Wistar
	Secretory Vesicles -- metabolism
	Synaptosomal-Associated Protein 25
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
Langue:	Anglais
Identificateurs:	urn:issn:0021-9258
	info:doi/10.1074/jbc.C400360200
	info:pii/C400360200
	info:scp/4744375389
	info:pmid/15319424