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High glucose and hydrogen peroxide increase c-Myc and haeme-oxygenase 1 mRNA levels in rat pancreatic islets without activating NFkappaB.

par Elouil, H.;Cardozo, Alessandra K ;Eizirik, Decio L. ;Henquin, Jean Claude;Jonas, John Joseph
Référence Diabetologia, 48, 3, page (496-505)
Publication Publié, 2005

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Titre:	High glucose and hydrogen peroxide increase c-Myc and haeme-oxygenase 1 mRNA levels in rat pancreatic islets without activating NFkappaB.
Auteur:	Elouil, H.; Cardozo, Alessandra K; Eizirik, Decio L.; Henquin, Jean Claude; Jonas, John Joseph
Informations sur la publication:	Diabetologia, 48, 3, page (496-505)
Statut de publication:	Publié, 2005
Sujet CREF:	Sciences bio-médicales et agricoles
Mots-clés:	Antioxidant
	Glucose toxicity
	NFκB
	Oxidative stress
	Pancreatic beta cell
MeSH keywords:	Animals
	Glucose -- pharmacology
	Heme Oxygenase (Decyclizing) -- genetics
	Heme Oxygenase-1
	Hydrogen Peroxide -- pharmacology
	Islets of Langerhans -- drug effects
	Islets of Langerhans -- metabolism
	MAP Kinase Signaling System -- drug effects
	MAP Kinase Signaling System -- physiology
	NF-kappa B -- metabolism
	Proto-Oncogene Proteins c-myc -- genetics
	RNA, Messenger -- drug effects
	RNA, Messenger -- genetics
	Rats
	Transcription, Genetic -- drug effects
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
Langue:	Anglais
Identificateurs:	urn:issn:0012-186X
	info:doi/10.1007/s00125-004-1664-4
	info:scp/16844377896
	info:pmid/15739117