Titre:
  • Cell loss during pseudoislet formation hampers profound improvements in islet lentiviral transduction efficacy for transplantation purposes.
Auteur:Callewaert, Hanne; Gysemans, Conny; Cardozo, Alessandra K; Elsner, M.; Tiedge, Markus; Eizirik, Decio L.; Mathieu, Chantal
Informations sur la publication:Cell transplantation, 16, 5, page (527-537)
Statut de publication:Publié, 2007
Sujet CREF:Sciences bio-médicales et agricoles
Mots-clés:Gene therapy
Islet transplantation
Lentiviral vector
Pancreatic β-cells
Pseudoislet aggregates
Type 1 diabetes
MeSH keywords:Animals
Cell Aggregation -- drug effects
Cell Death -- drug effects
Cell Line
Cell Separation
Cell Survival -- drug effects
Cytokines -- pharmacology
Flow Cytometry
Humans
Insulin -- secretion
Islets of Langerhans -- cytology
Islets of Langerhans -- drug effects
Islets of Langerhans -- secretion
Islets of Langerhans Transplantation
Lentivirus -- genetics
Male
Mice
Rats
Rats, Wistar
Time Factors
Transduction, Genetic
Transgenes
Note générale:Journal Article
Research Support, Non-U.S. Gov't
Langue:Anglais
Identificateurs:urn:issn:0963-6897
info:scp/34548427326
info:pmid/17708342