Titre:
  • cAMP analog mapping of Epac1 and cAMP kinase. Discriminating analogs demonstrate that Epac and cAMP kinase act synergistically to promote PC-12 cell neurite extension.
Auteur:Christensen, Anne E; Selheim, Frode; de Rooij, Johan; Dremier, Sarah; Schwede, Frank; Dao, Khanh K; Martinez, Aurora; Maenhaut, Carine; Bos, Johannes L; Genieser, H-G; Døskeland, Stein O
Informations sur la publication:The Journal of biological chemistry, 278, 37, page (35394-35402)
Statut de publication:Publié, 2003-09
Sujet CREF:Sciences bio-médicales et agricoles
MeSH keywords:Cyclic AMP -- analogs & derivatives
Cyclic AMP -- metabolism
Cyclic AMP-Dependent Protein Kinases -- metabolism
Cyclic GMP -- analogs & derivatives
Cyclic GMP -- metabolism
Enzyme Activation
Guanine Nucleotide Exchange Factors -- chemistry
Guanine Nucleotide Exchange Factors -- metabolism
Kinetics
Models, Molecular
Peptide Fragments -- chemistry
Peptide Fragments -- metabolism
Protein Conformation
Recombinant Fusion Proteins -- metabolism
Substrate Specificity
Note générale:Journal Article
Research Support, Non-U.S. Gov't
Langue:Anglais
Identificateurs:urn:issn:0021-9258
info:doi/10.1074/jbc.M302179200
info:pii/M302179200
info:scp/0041315574
info:pmid/12819211
VX-003771