Titre:
  • A lactosylated steroid contributes in vivo therapeutic benefits in experimental models of mouse lymphoma and human glioblastoma.
Auteur:Ingrassia, Laurent; Nshimyumukiza, Prosper; Dewelle, Janique; Lefranc, Florence; Wlodarczak, Lise; Thomas, Stéphanie; Dielie, Gwenaël; Chiron, Christelle; Zedde, Chantal; Tisnès, Pierre; van Soest, Rob; Braekman, Jean Claude; Darro, Francis; Kiss, Robert
Informations sur la publication:Journal of medicinal chemistry, 49, 5, page (1800-1807)
Statut de publication:Publié, 2006-03
Sujet CREF:Sciences bio-médicales et agricoles
MeSH keywords:Animals
Antineoplastic Agents -- chemical synthesis
Antineoplastic Agents -- chemistry
Antineoplastic Agents -- pharmacology
Brain Neoplasms -- drug therapy
Brain Neoplasms -- mortality
Brain Neoplasms -- pathology
Cell Line, Tumor
Cell Movement -- drug effects
Cisplatin -- pharmacology
Drug Screening Assays, Antitumor
Drug Synergism
Fucose -- chemistry
Glioblastoma -- drug therapy
Glioblastoma -- mortality
Glioblastoma -- pathology
Glycosylation
Humans
Immunocompromised Host
Lactose -- chemistry
Lymphoma -- drug therapy
Lymphoma -- mortality
Lymphoma -- pathology
Mice
Neoplasm Transplantation
Steroids -- chemical synthesis
Steroids -- chemistry
Steroids -- pharmacology
Structure-Activity Relationship
Survival Rate
Transplantation, Heterologous
Note générale:Journal Article
Research Support, Non-U.S. Gov't
Langue:Anglais
Identificateurs:urn:issn:0022-2623
info:doi/10.1021/jm050971v
info:scp/33644861554
info:pmid/16509595