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4-IBP, a sigma1 receptor agonist, decreases the migration of human cancer cells, including glioblastoma cells, in vitro and sensitizes them in vitro and in vivo to cytotoxic insults of proapoptotic and proautophagic drugs.

par Megalizzi, Véronique ;Mathieu, Véronique ;Mijatovic, Tatjana ;Gailly, Philippe;Debeir, Olivier ;De Nève, Nancy;Van Damme, Marc ;Bontempi, Gianluca ;Haibe-Kains, Benjamin ;Decaestecker, Christine ;Kondo, Yasuko;Kiss, Robert ;Lefranc, Florence
Référence Neoplasia (New York, N.Y.), 9, 5, page (358-369)
Publication Publié, 2007-05

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Titre:	4-IBP, a sigma1 receptor agonist, decreases the migration of human cancer cells, including glioblastoma cells, in vitro and sensitizes them in vitro and in vivo to cytotoxic insults of proapoptotic and proautophagic drugs.
Auteur:	Megalizzi, Véronique; Mathieu, Véronique; Mijatovic, Tatjana; Gailly, Philippe; Debeir, Olivier; De Nève, Nancy; Van Damme, Marc; Bontempi, Gianluca; Haibe-Kains, Benjamin; Decaestecker, Christine; Kondo, Yasuko; Kiss, Robert; Lefranc, Florence
Informations sur la publication:	Neoplasia (New York, N.Y.), 9, 5, page (358-369)
Statut de publication:	Publié, 2007-05
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	Actins -- chemistry
	Animals
	Antineoplastic Agents -- pharmacology
	Apoptosis -- drug effects
	Autophagy -- drug effects
	Benzamides -- pharmacology
	Calcium -- metabolism
	Cell Line, Tumor
	Cell Movement -- drug effects
	Endoplasmic Reticulum -- drug effects
	Female
	Glioblastoma -- drug therapy
	Glioblastoma -- pathology
	Guanine Nucleotide Dissociation Inhibitors -- physiology
	Humans
	Mice
	Neoplasm Transplantation
	Piperidines -- pharmacology
	Receptors, sigma -- agonists
	Receptors, sigma -- physiology
	Transplantation, Heterologous
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
Langue:	Anglais
Identificateurs:	urn:issn:1476-5586
	info:pmid/17534441
	PMC1877975