Titre:
  • Knocking down galectin 1 in human hs683 glioblastoma cells impairs both angiogenesis and endoplasmic reticulum stress responses.
Auteur:Le Mercier, Marie; Mathieu, Véronique; Haibe-Kains, Benjamin; Bontempi, Gianluca; Mijatovic, Tatjana; Decaestecker, Christine; Kiss, Robert; Lefranc, Florence
Informations sur la publication:Journal of neuropathology and experimental neurology, 67, 5, page (456-469)
Statut de publication:Publié, 2008-05
Sujet CREF:Sciences bio-médicales et agricoles
Mots-clés:Angiogenesis
Endoplasmic reticulum stress
Galectin 1
Glioblastoma
Hypoxia
MeSH keywords:Animals
Antineoplastic Agents, Alkylating -- pharmacology
Brain Neoplasms -- genetics
Brain Neoplasms -- metabolism
Brain Neoplasms -- therapy
Cell Line, Tumor
Dacarbazine -- analogs & derivatives
Dacarbazine -- pharmacology
Down-Regulation -- drug effects
Down-Regulation -- genetics
Endoplasmic Reticulum -- drug effects
Endoplasmic Reticulum -- genetics
Endoplasmic Reticulum -- metabolism
Endoribonucleases -- drug effects
Endoribonucleases -- genetics
Endoribonucleases -- metabolism
Female
Galectin 1 -- genetics
Gene Expression Regulation, Neoplastic -- drug effects
Gene Expression Regulation, Neoplastic -- genetics
Gene Silencing -- physiology
Gene Therapy -- methods
Glioblastoma -- genetics
Glioblastoma -- metabolism
Glioblastoma -- therapy
HSP40 Heat-Shock Proteins -- drug effects
HSP40 Heat-Shock Proteins -- genetics
HSP40 Heat-Shock Proteins -- metabolism
Humans
Membrane Proteins -- drug effects
Membrane Proteins -- genetics
Membrane Proteins -- metabolism
Mice
Molecular Chaperones -- drug effects
Molecular Chaperones -- genetics
Molecular Chaperones -- metabolism
Neovascularization, Pathologic -- genetics
Neovascularization, Pathologic -- metabolism
Neovascularization, Pathologic -- therapy
Oxidative Stress -- genetics
Protein-Serine-Threonine Kinases -- drug effects
Protein-Serine-Threonine Kinases -- genetics
Protein-Serine-Threonine Kinases -- metabolism
Proteins -- drug effects
Proteins -- genetics
Proteins -- metabolism
RNA Interference -- drug effects
RNA Interference -- physiology
RNA, Small Interfering -- genetics
RNA, Small Interfering -- pharmacology
RNA, Small Interfering -- therapeutic use
Signal Transduction -- genetics
Transplantation, Heterologous
Note générale:Journal Article
Research Support, Non-U.S. Gov't
Langue:Anglais
Identificateurs:urn:issn:0022-3069
info:doi/10.1097/NEN.0b013e318170f892
info:scp/43249107550
info:pmid/18431251