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Structure-activity relationship analysis of novel derivatives of narciclasine (an Amaryllidaceae isocarbostyril derivative) as potential anticancer agents.

par Ingrassia, Laurent ;Lefranc, Florence ;Dewelle, Janique;Pottier, Laurent ;Mathieu, Véronique ;Spiegl-Kreinecker, Sabine;Sauvage, Sébastien ;El Yazidi, Mohamed ;Dehoux, Mischaël ;Berger, Walter;Van Quaquebeke, Eric ;Kiss, Robert
Référence Journal of medicinal chemistry, 52, 4, page (1100-1114)
Publication Publié, 2009-02

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Titre:	Structure-activity relationship analysis of novel derivatives of narciclasine (an Amaryllidaceae isocarbostyril derivative) as potential anticancer agents.
Auteur:	Ingrassia, Laurent; Lefranc, Florence; Dewelle, Janique; Pottier, Laurent; Mathieu, Véronique; Spiegl-Kreinecker, Sabine; Sauvage, Sébastien; El Yazidi, Mohamed; Dehoux, Mischaël; Berger, Walter; Van Quaquebeke, Eric; Kiss, Robert
Informations sur la publication:	Journal of medicinal chemistry, 52, 4, page (1100-1114)
Statut de publication:	Publié, 2009-02
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	Amaryllidaceae Alkaloids -- chemistry
	Amaryllidaceae Alkaloids -- pharmacology
	Animals
	Antineoplastic Agents -- chemistry
	Antineoplastic Agents -- pharmacology
	Cell Proliferation
	Drug Administration Routes
	Drug Stability
	Glioma -- drug therapy
	Humans
	Mice
	Phenanthridines -- chemistry
	Phenanthridines -- pharmacology
	Structure-Activity Relationship
	Xenograft Model Antitumor Assays
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
	SCOPUS: ar.j
Langue:	Anglais
Identificateurs:	urn:issn:0022-2623
	info:doi/10.1021/jm8013585
	info:pii/10.1021/jm8013585
	info:scp/64349093471
	info:pmid/19199649