Titre:
  • Screening of anti-glioma effects induced by sigma-1 receptor ligands: potential new use for old anti-psychiatric medicines.
Auteur:Megalizzi, Véronique; Decaestecker, Christine; Debeir, Olivier; Spiegl-Kreinecker, Sabine; Berger, Walter; Lefranc, Florence; Kast, Richard E; Kiss, Robert
Informations sur la publication:European journal of cancer, 45, 16, page (2893-2905)
Statut de publication:Publié, 2009-11
Sujet CREF:Sciences bio-médicales et agricoles
Mots-clés:Cell migration
Cell proliferation
Chemotherapy
Donepezil
Glioblastoma
Mitotic arrest
Sigma receptors
MeSH keywords:Animals
Antimitotic Agents -- pharmacology
Antineoplastic Agents -- chemistry
Antineoplastic Agents -- pharmacology
Brain Neoplasms -- drug therapy
Cell Proliferation -- drug effects
Central Nervous System Agents -- chemistry
Central Nervous System Agents -- pharmacology
Drug Screening Assays, Antitumor
Female
Glioblastoma -- drug therapy
Humans
Mice
Mice, Inbred Strains
Neoplasm Transplantation
Receptors, sigma -- agonists
Receptors, sigma -- antagonists & inhibitors
Tumor Cells, Cultured
Note générale:Journal Article
Research Support, Non-U.S. Gov't
Langue:Anglais
Identificateurs:urn:issn:0959-8049
info:doi/10.1016/j.ejca.2009.07.011
info:pii/S0959-8049(09)00548-6
info:scp/70350020952
info:pmid/19679463