Titre:
  • Signaling by IL-1beta+IFN-gamma and ER stress converge on DP5/Hrk activation: a novel mechanism for pancreatic beta-cell apoptosis.
Auteur:Gurzov, Esteban Nicolas; Ortis, Fernanda; Andrade Da Cunha, Daniel; Gosset, Geoffrey; Li, M; Cardozo, Alessandra K; Eizirik, Decio L.
Informations sur la publication:Cell death and differentiation, 16, 11, page (1539-1550)
Statut de publication:Publié, 2009
Sujet CREF:Sciences bio-médicales et agricoles
MeSH keywords:Animals
Apoptosis
Apoptosis Regulatory Proteins -- metabolism
Cytochromes c -- metabolism
Endoplasmic Reticulum -- metabolism
Insulin-Secreting Cells -- cytology
Insulin-Secreting Cells -- metabolism
Interferon-gamma -- pharmacology
Interleukin-1beta -- pharmacology
JNK Mitogen-Activated Protein Kinases -- metabolism
Neuropeptides -- metabolism
RNA, Small Interfering -- metabolism
Rats
Rats, Wistar
Signal Transduction
Up-Regulation
Note générale:Journal Article
Research Support, Non-U.S. Gov't
Langue:Anglais
Identificateurs:urn:issn:1350-9047
info:doi/10.1038/cdd.2009.99
info:pii/cdd200999
info:scp/70350028224
info:pmid/19629134