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Double-stranded RNA induces pancreatic beta-cell apoptosis by activation of the toll-like receptor 3 and interferon regulatory factor 3 pathways.

par Dogusan, Zeynep ;García, Mónica;Flamez, Daisy ;Alexopoulou, Lena;Goldman, Michel ;Gysemans, Conny;Mathieu, Chantal;Libert, Claude;Eizirik, Decio L. ;Rasschaert, Joanne
Référence Diabetes (New York, N.Y.), 57, 5, page (1236-1245)
Publication Publié, 2008

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Titre:	Double-stranded RNA induces pancreatic beta-cell apoptosis by activation of the toll-like receptor 3 and interferon regulatory factor 3 pathways.
Auteur:	Dogusan, Zeynep; García, Mónica; Flamez, Daisy; Alexopoulou, Lena; Goldman, Michel; Gysemans, Conny; Mathieu, Chantal; Libert, Claude; Eizirik, Decio L.; Rasschaert, Joanne
Informations sur la publication:	Diabetes (New York, N.Y.), 57, 5, page (1236-1245)
Statut de publication:	Publié, 2008
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	Animals
	Cell Survival
	Cells, Cultured
	Insulin-Secreting Cells -- cytology
	Insulin-Secreting Cells -- physiology
	Interferon Regulatory Factor-3 -- physiology
	Interferon-beta -- biosynthesis
	Male
	Mice
	Mice, Inbred C57BL
	Mice, Knockout
	Poly I-C -- pharmacology
	RNA, Double-Stranded -- genetics
	Rats
	Rats, Wistar
	Reverse Transcriptase Polymerase Chain Reaction
	Toll-Like Receptor 3 -- deficiency
	Toll-Like Receptor 3 -- genetics
	Toll-Like Receptor 3 -- physiology
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
Langue:	Anglais
Identificateurs:	urn:issn:0012-1797
	info:doi/10.2337/db07-0844
	info:pii/db07-0844
	info:scp/48449098774
	info:pmid/18223009