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Human IL-12(p35) gene activation involves selective remodeling of a single nucleosome within a region of the promoter containing critical Sp1-binding sites.

par Goriely, Stanislas ;Demonte, Dominique ;Nizet, Séverine;De Wit, Dominique ;Willems, Fabienne ;Goldman, Michel ;Van Lint, Carine
Référence Blood, 101, 12, page (4894-4902)
Publication Publié, 2003

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Titre:	Human IL-12(p35) gene activation involves selective remodeling of a single nucleosome within a region of the promoter containing critical Sp1-binding sites.
Auteur:	Goriely, Stanislas; Demonte, Dominique; Nizet, Séverine; De Wit, Dominique; Willems, Fabienne; Goldman, Michel; Van Lint, Carine
Informations sur la publication:	Blood, 101, 12, page (4894-4902)
Statut de publication:	Publié, 2003
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	Base Sequence
	Binding Sites
	Cell Line
	DNA -- chemistry
	DNA -- metabolism
	Dendritic Cells -- ultrastructure
	Deoxyribonuclease EcoRI -- metabolism
	Deoxyribonuclease I -- metabolism
	Gene Expression Regulation -- drug effects
	Humans
	Interferon-gamma -- pharmacology
	Interleukin-12 -- genetics
	Lipopolysaccharides -- pharmacology
	Luciferases -- genetics
	Micrococcal Nuclease -- metabolism
	Molecular Sequence Data
	Monocytes -- ultrastructure
	Nucleosomes -- chemistry
	Nucleosomes -- ultrastructure
	Promoter Regions, Genetic -- genetics
	RNA, Messenger -- biosynthesis
	Reverse Transcriptase Polymerase Chain Reaction
	Sp1 Transcription Factor -- metabolism
	Transcriptional Activation
	Transfection
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
Langue:	Anglais
Identificateurs:	urn:issn:0006-4971
	info:doi/10.1182/blood-2002-09-2851
	info:pii/2002-09-2851
	info:scp/0038115124
	info:pmid/12576336