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Pharmacological inhibition of nicotinamide phosphoribosyltransferase/visfatin enzymatic activity identifies a new inflammatory pathway linked to NAD.

par Busso, Nathalie;Karababa, Mahir;Nobile, Massimo;Rolaz, Aline;Van Gool, Frédéric ;Galli, Mara ;Leo, Oberdan ;So, Alexander;De Smedt, Thibaut
Référence PloS one, 3, 5, page (e2267)
Publication Publié, 2008

Article révisé par les pairs

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Titre:	Pharmacological inhibition of nicotinamide phosphoribosyltransferase/visfatin enzymatic activity identifies a new inflammatory pathway linked to NAD.
Auteur:	Busso, Nathalie; Karababa, Mahir; Nobile, Massimo; Rolaz, Aline; Van Gool, Frédéric; Galli, Mara; Leo, Oberdan; So, Alexander; De Smedt, Thibaut
Informations sur la publication:	PloS one, 3, 5, page (e2267)
Statut de publication:	Publié, 2008
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	Animals
	Arthritis, Experimental -- enzymology
	Collagen -- administration & dosage
	Enzyme Inhibitors -- pharmacology
	Female
	Humans
	Inflammation -- enzymology
	Male
	Mice
	Mice, Inbred C57BL
	Mice, Inbred DBA
	NAD -- metabolism
	Nicotinamide Phosphoribosyltransferase -- antagonists & inhibitors
	Nicotinamide Phosphoribosyltransferase -- metabolism
	Tumor Necrosis Factor-alpha -- blood
	Up-Regulation
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
Langue:	Anglais
Identificateurs:	urn:issn:1932-6203
	info:doi/10.1371/journal.pone.0002267
	info:scp/48249105497
	info:pmid/18493620
	PMC2377336