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Genetically resistant mice lacking MyD88-adapter protein display a high susceptibility to Leishmania major infection associated with a polarized Th2 response.

par Muraille, Eric ;De Trez, Carl ;Brait, Maryse ;De Baetselier, Patrick;Leo, Oberdan ;Carlier, Yves
Référence The Journal of immunology, 170, 8, page (4237-4241)
Publication Publié, 2003-04

Article révisé par les pairs

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Titre:	Genetically resistant mice lacking MyD88-adapter protein display a high susceptibility to Leishmania major infection associated with a polarized Th2 response.
Auteur:	Muraille, Eric; De Trez, Carl; Brait, Maryse; De Baetselier, Patrick; Leo, Oberdan; Carlier, Yves
Informations sur la publication:	The Journal of immunology, 170, 8, page (4237-4241)
Statut de publication:	Publié, 2003-04
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	Adaptor Proteins, Signal Transducing
	Animals
	Antigens, Differentiation -- genetics
	Antigens, Differentiation -- physiology
	Cell Differentiation -- genetics
	Cell Differentiation -- immunology
	Crosses, Genetic
	Female
	Genetic Predisposition to Disease
	Immunity, Innate -- genetics
	Injections, Intraperitoneal
	Interferon-gamma -- biosynthesis
	Interleukin-12 -- administration & dosage
	Interleukin-4 -- biosynthesis
	Leishmania major -- immunology
	Leishmaniasis, Cutaneous -- genetics
	Leishmaniasis, Cutaneous -- immunology
	Mice
	Mice, Inbred BALB C
	Mice, Inbred C57BL
	Mice, Knockout
	Myeloid Differentiation Factor 88
	Receptors, Immunologic -- deficiency
	Receptors, Immunologic -- genetics
	Receptors, Immunologic -- physiology
	Signal Transduction -- genetics
	Signal Transduction -- immunology
	Th2 Cells -- cytology
	Th2 Cells -- immunology
	Th2 Cells -- metabolism
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
Langue:	Anglais
Identificateurs:	urn:issn:0022-1767
	info:pmid/12682257