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Disruption of the gamma-interferon signaling pathway at the level of signal transducer and activator of transcription-1 prevents immune destruction of beta-cells.

par Gysemans, Conny A;Ladrière, Laurence ;Callewaert, Hanne;Rasschaert, Joanne ;Flamez, Daisy ;Levy, David E;Matthys, Patrick;Eizirik, Decio L. ;Mathieu, Chantal
Référence Diabetes (New York, N.Y.), 54, 8, page (2396-2403)
Publication Publié, 2005

Article révisé par les pairs

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Titre:	Disruption of the gamma-interferon signaling pathway at the level of signal transducer and activator of transcription-1 prevents immune destruction of beta-cells.
Auteur:	Gysemans, Conny A; Ladrière, Laurence; Callewaert, Hanne; Rasschaert, Joanne; Flamez, Daisy; Levy, David E; Matthys, Patrick; Eizirik, Decio L.; Mathieu, Chantal
Informations sur la publication:	Diabetes (New York, N.Y.), 54, 8, page (2396-2403)
Statut de publication:	Publié, 2005
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	Animals
	Apoptosis
	Cell Survival
	Cytokines -- pharmacology
	DNA-Binding Proteins -- deficiency
	DNA-Binding Proteins -- physiology
	Diabetes Mellitus, Experimental -- immunology
	Female
	Gene Expression -- drug effects
	Insulin -- secretion
	Interferon-gamma -- pharmacology
	Interferon-gamma -- physiology
	Interleukin-1 -- pharmacology
	Islets of Langerhans -- cytology
	Islets of Langerhans -- immunology
	Male
	Mice
	Mice, Knockout
	STAT1 Transcription Factor
	Signal Transduction
	Trans-Activators -- deficiency
	Trans-Activators -- physiology
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
Langue:	Anglais
Identificateurs:	urn:issn:0012-1797
	info:pii/54/8/2396
	info:pmid/16046307