Titre:
  • Knockout mice reveal a role for P2Y6 receptor in macrophages, endothelial cells, and vascular smooth muscle cells.
Auteur:Bar, Isabelle; Guns, Pieter-Jan D F; Metallo, Jessica; Cammarata, Dorothée; Wilkin, Françoise; Boeynaems, Jean-Marie; Bult, Hidde; Robaye, Bernard
Informations sur la publication:Molecular pharmacology, 74, 3, page (777-784)
Statut de publication:Publié, 2008-09
Sujet CREF:Sciences bio-médicales et agricoles
MeSH keywords:Animals
Aorta -- drug effects
Aorta -- metabolism
Cytokines -- biosynthesis
Endothelial Cells -- drug effects
Endothelial Cells -- metabolism
Extracellular Signal-Regulated MAP Kinases -- metabolism
Gene Deletion
Gene Expression Regulation -- drug effects
Inositol Phosphates -- biosynthesis
Lipopolysaccharides -- pharmacology
MAP Kinase Signaling System -- drug effects
Macrophages, Peritoneal -- drug effects
Macrophages, Peritoneal -- enzymology
Macrophages, Peritoneal -- metabolism
Mice
Mice, Knockout
Muscle Contraction -- drug effects
Muscle Relaxation -- drug effects
Muscle, Smooth, Vascular -- cytology
Myocytes, Smooth Muscle -- drug effects
Myocytes, Smooth Muscle -- metabolism
Nucleotides -- pharmacology
Phenylephrine -- pharmacology
RNA, Messenger -- genetics
RNA, Messenger -- metabolism
Receptors, Purinergic P2 -- genetics
Receptors, Purinergic P2 -- metabolism
Thioglycolates -- pharmacology
Vasomotor System -- drug effects
Note générale:Comparative Study
Journal Article
Research Support, Non-U.S. Gov't
Langue:Anglais
Identificateurs:urn:issn:0026-895X
info:doi/10.1124/mol.108.046904
info:pii/mol.108.046904
info:scp/50449096581
info:pmid/18523137