Titre:
  • Synthesis and structure-activity relationships of suramin-derived P2Y11 receptor antagonists with nanomolar potency.
Auteur:Ullmann, Heiko; Meis, Sabine; Hongwiset, Darunee; Marzian, Claudia; Wiese, Michael; Nickel, Peter; Communi, Didier; Boeynaems, Jean-Marie; Wolf, Christian; Hausmann, Ralf; Schmalzing, Günther; Kassack, Matthias U
Informations sur la publication:Journal of medicinal chemistry, 48, 22, page (7040-7048)
Statut de publication:Publié, 2005-11
Sujet CREF:Sciences bio-médicales et agricoles
MeSH keywords:Animals
Calcium -- metabolism
Cell Line
Electrophysiology
Humans
Oocytes -- drug effects
Oocytes -- physiology
Quantitative Structure-Activity Relationship
Rats
Receptors, Purinergic P2 -- antagonists & inhibitors
Receptors, Purinergic P2 -- genetics
Receptors, Purinergic P2 -- physiology
Reverse Transcriptase Polymerase Chain Reaction
Suramin -- analogs & derivatives
Suramin -- chemical synthesis
Suramin -- pharmacology
Transfection
Xenopus laevis
Note générale:Journal Article
Research Support, Non-U.S. Gov't
Langue:Anglais
Identificateurs:urn:issn:0022-2623
info:doi/10.1021/jm050301p
info:scp/27444436716
info:pmid/16250663