Postmastectomy radiation therapy in patients with human epidermal growth factor receptor 2 (HER2)-positive breast cancer: a retrospective exploratory cohort analysis of the adjuvant lapatinib and/or trastuzumab treatment optimization (ALTTO) trial [BIG 2-06/NCCTG N063D (Alliance)].

De Santis, Maria Carmen; Campbell, Christine; Samy, Faye; De Rose, Fiorenza; Meduri, Bruno; Lambertini, Matteo; Sotiriou, Christos; Carnevale, Maria Grazia; Ferro, Antonella; Saura, Cristina; Choudhury, Anup; Giandini, Carlotta; Verderio, Paolo; Chumsri, Saranya; Appierto, Valentina; Piccart, Martine; Pruneri, Giancarlo; Colciago, Riccardo Ray; de Azambuja, Evandro; Di Cosimo, Serena

doi:doi/10.1016/j.eclinm.2026.104079

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Article révisé par les pairs

Résumé :

Postmastectomy radiation therapy (PMRT) improves locoregional control and survival in patients with early breast cancer, but it is unclear whether these benefits extend to human epidermal growth factor receptor 2 (HER2)-positive patients in the anti-HER2 era.

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