Titre:
  • The diabetes-associated K+ channel TALK-2 controls human beta cell endoplasmic reticulum Ca2+ handling, which promotes basal insulin release and limits glucose-stimulated insulin secretion
Auteur:Dobson, Jordyn J.R.; Dadi, Prasanna P.K.; Dickerson, Matthew Thomas; Nakhe, Arya A.Y.; Behera, Soma; Gibson, Shannon S.E.; Peachee, Spencer S.J.; Piron, Anthony; Cnop, Miriam; Jacobson, David Aaron
Informations sur la publication:Diabetologia
Statut de publication:Publié, 2026
Sujet CREF:Médecine interne
Endocrinologie
Diabétologie
Métabolisme
Mots-clés:Beta cell
Ca2+
ER
Insulin secretion
Ion channels
Islet
K2P
Live cell imaging
Single nucleotide polymorphisms
Type 2 diabetes
Note générale:SCOPUS: ar.j
Langue:Anglais
Identificateurs:urn:issn:0012-186X
info:doi/10.1007/s00125-026-06683-9
info:scp/105031051411