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Vinylsiloxanes as Alkenylating Agents in Nickel-Catalyzed Difunctionalization of Vinylarenes

par Salamone, Logan;Tan, Qihang ;Evano, Gwilherm ;Riant, Olivier
Référence Organic letters, 28
Publication Publié, 2026-04-21

Article révisé par les pairs

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Résumé :

We report the first directing-group-free nickel-catalyzed difunctionalization of vinylarenes using bench-stable vinylsiloxanes as alkenylating agents. This mild, scalable and stereospecific method provides regioselective access to functionalized disubstituted alkenes with broad scope, low catalyst loadings, and minimal Z-isomerization, establishing vinylsiloxanes as versatile alkenyl transfer partners in multicomponent nickel catalysis.