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Complete remission with olaparib in BRIP1-mutated metastatic high-grade pleomorphic sarcoma: case study and literature review – an example of a genomic profiling-based tumor treatment, in a cancer type with high unmet clinical need

par Thooft, Alexander A.D.J.;Joris, S.;Jacobs, Celine;Creytens, David H K V D.H.;Rottey, Sylvie;Maes, Brigitte;Aftimos, Philippe ;Lapeire, Lore
Référence Acta oncologica, 64, page (1295-1306)
Publication Publié, 2025

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Titre:	Complete remission with olaparib in BRIP1-mutated metastatic high-grade pleomorphic sarcoma: case study and literature review – an example of a genomic profiling-based tumor treatment, in a cancer type with high unmet clinical need
Auteur:	Thooft, Alexander A.D.J.; Joris, S.; Jacobs, Celine; Creytens, David H K V D.H.; Rottey, Sylvie; Maes, Brigitte; Aftimos, Philippe; Lapeire, Lore
Informations sur la publication:	Acta oncologica, 64, page (1295-1306)
Statut de publication:	Publié, 2025
Sujet CREF:	Imagerie médicale, radiologie, tomographie
	Hématologie
	Cancérologie
Mots-clés:	BRIP1 protein
	high-throughput nucleotide sequencing
	human
	poly(ADP-ribose) polymerase inhibitors
	precision medicine
	recombinational DNA repair
	remission induction
	sarcoma
Note générale:	SCOPUS: re.j
Langue:	Anglais
Identificateurs:	urn:issn:0284-186X
	info:doi/10.2340/1651-226X.2025.43374
	info:scp/105017101608
	info:pmid/40988318