par Salvagno, Michele ;Taccone, Fabio Silvio
Référence Encyclopedia of the Neurological Sciences, Elsevier, page (V2:590-V2:603)
Publication Publié, 2025-01
Partie d'ouvrage collectif
Résumé : Anemia is common among critically ill patients and has been associated with poor outcomes. In acute brain-injured patients, anemia can also induce secondary damage, as the injured brain is at heightened vulnerability to reduced oxygen delivery. Therefore, managing these patients requires careful consideration and additional measures kurato balance the benefits and risks associated with red blood cell transfusions (RBCT). This article explores the role of hemoglobin in oxygen transport, the pathophysiology of anemia in neuro-critical patients, and its impact on cerebral function. It also addresses the complexity involved in transfusion strategies for managing anemia in patients with acute brain injuries, emphasizing the importance of determining appropriate transfusion thresholds peculiar to these patients and reviewing current evidence on optimizing cerebral oxygen delivery. Individualized strategies are crucial, and multimodal neuromonitoring, including brain oxygenation, can aid in managing anemia in these patients.