Article révisé par les pairs
Titre:
  • A TCF4-dependent gene regulatory network confers resistance to immunotherapy in melanoma
Auteur:Pozniak, Joanna; Pedri, Dennis; Landeloos, Ewout; Van Herck, Yannick; Antoranz, Asier; Vanwynsberghe, Lukas; Nowosad, Ada; Roda, Niccolò; Makhzami, Samira; Bervoets, Greet; Maciel, Lucas Ferreira; Pulido-Vicuña, Carlos Ariel; Pollaris, Lotte; Seurinck, Ruth; Zhao, Fang; Flem-Karlsen, Karine; Damsky, William; Chen, Limin; Karagianni, Despoina; Cinque, Sonia; Kint, Sam; Vandereyken, Katy; Rombaut, Benjamin; Voet, T.; Vernaillen, Frank; Annaert, Wim; Lambrechts, Diether; Boecxstaens, Veerle; Saeys, Yvan; van den Oord, Joost; Bosisio, Francesca; Karras, Panagiotis; Shain, Alan Hunter; Bosenberg, Marcus; Leucci, Eleonora; Paschen, Annette; Rambow, Florian; Bechter, Oliver; Marine, Jean-Christophe
Informations sur la publication:Cell, 187, 1, page (166-183.e25)
Statut de publication:Publié, 2024-01-01
Sujet CREF:Biologie
Mots-clés:antigen presentation
BET inhibition
checkpoint immunotherapy
dedifferentiation
EMT
intra-tumor heterogeneity
melanoma
single-cell transcriptomics
TCF4
tumor microenvironment
Note générale:SCOPUS: ar.j
Langue:Anglais
Identificateurs:urn:issn:0092-8674
info:doi/10.1016/j.cell.2023.11.037
info:pii/S0092867423013223
info:scp/85181248786
info:pmid/38181739

Documents en relation

DI-fusion

  • A TCF4/BRD4-dependent regulatory network confers cross-resistance to targeted and immune checkpoint therapy in melanoma
    par Pozniak, Joanna , Pedri, Dennis , Landeloos, Ewout , Van Herck, Yannick , Antoranz, Asier , Karras, Panagiotis , Nowosad, Ada , Makhzami, Samira , Bervoets, Greet , Dewaele, Michael , Vanwynsberghe, Lukas , Cinque, Sonia , Kint, Sam , Vandereyken, Katy , Voet, Thierry , Vernaillen, Frank , Annaert, Wim , Lambrechts, Diether , Boecxstaens, Veerle , van den Oord, Joost , Bosisio, Francesca , Leucci, Eleonora , Rambow, Florian , Bechter, Oliver , Marine, Jean-Christophe
    Publication 2022-08-13
  • Epithelial-to-mesenchymal-like transition events in melanoma
    par Pedri, Dennis , Karras, Panagiotis , Landeloos, Ewout , Marine, Jean-Christophe , Rambow, Florian
    Publication 2022-03-01
  • A cellular hierarchy in melanoma uncouples growth and metastasis
    par Karras, Panagiotis , Bordeu, Ignacio , Pozniak, Joanna , Nowosad, Ada , Pazzi, Cecilia , Van Raemdonck, Nina , Landeloos, Ewout , Van Herck, Yannick , Pedri, Dennis , Bervoets, Greet , Makhzami, Samira , Khoo, Jia Hui , Pavie, Benjamin , Lamote, Jochen , Marin-Bejar, Oskar , Dewaele, Michael , Liang, Han , Zhang, Xingju , Hua, Yichao , Wouters, Jasper , Browaeys, Robin , Bergers, Gabriele , Saeys, Yvan , Bosisio, Francesca , van den Oord, Joost , Lambrechts, Diether , Rustgi, Anil , Bechter, Oliver , Blanpain, Cédric , Simons, Benjamin D , Rambow, Florian , Marine, Jean-Christophe
    Publication 2022-10-01
  • Perivascular niches: critical hubs in cancer evolution
    par Nowosad, Ada , Marine, Jean-Christophe , Karras, Panagiotis
    Publication 2023-11-01
  • Perivascular niches dictate developmental cellular hierarchies during melanoma growth
    par Karras, Panagiotis , Bordeu, Ignacio , Pozniak, Joanna , Nowosad, Ada , Pazzi, Cecilia , Van Raemdonck, Nina , Landeloos, Ewout , Blanpain, Cédric , Rambow, Florian , Marine, Jean-Christophe
    Publication 2022-12-01