Titre:
  • Carboplatin and paclitaxel induced-gonadotoxicity on the ovarian reserve of young breast cancer patients with BRCA1 mutation.
Auteur:Dias Nunes, Joana; Ntemou, Elissavet; Van Den Steen, Géraldine; Findikli, Necati; Fastrez, Maxime; Delbaere, Anne; Lambertini, Matteo; Devos, Melody; Demeestere, Isabelle
Informations sur la publication:Human reproduction, 40, 9, page (1709-1719)
Statut de publication:Publié, 2025-09
Sujet CREF:Gynécologie
Cancérologie
Sciences biomédicales
Mots-clés:BRCA mutations
DNA damage
chemotherapy
fertility preservation
ovarian tissue
MeSH keywords:Female
Carboplatin -- adverse effects -- therapeutic use
Paclitaxel -- adverse effects
Humans
Ovarian Reserve -- drug effects
Animals
Breast Neoplasms -- genetics -- drug therapy
Adult
BRCA1 Protein -- genetics
Ovary -- drug effects
Mice
Germ-Line Mutation
Ovarian Follicle -- drug effects
Antineoplastic Agents -- adverse effects
Genes, BRCA1
Langue:Anglais
Identificateurs:urn:issn:0268-1161
info:doi/10.1093/humrep/deaf133
info:pii/8196984
info:pmid/40646715