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Pelophen B is a non-taxoid binding microtubule-stabilizing agent with promising preclinical anticancer properties.

par Vermeulen, Stephanie;Ernst, Sam;Blondeel, Eva;Xia, Zihan;Rappu, Pekka;Heino, Jyrki;Dedeyne, Sándor;Denys, Hannelore;Sys, Gwen;Gijsels, Stefanie;Depypere, Herman T.;Tummers, Philippe;Ceelen, Wim;Craciun, Ligia;Demetter, Pieter ;Raes, Olivier;Hendrix, An;Van der Eycken, Johan;De Wever, Olivier
Référence Scientific reports, 14, 1, page (30188)
Publication Publié, 2024-12-01

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Titre:	Pelophen B is a non-taxoid binding microtubule-stabilizing agent with promising preclinical anticancer properties.
Auteur:	Vermeulen, Stephanie; Ernst, Sam; Blondeel, Eva; Xia, Zihan; Rappu, Pekka; Heino, Jyrki; Dedeyne, Sándor; Denys, Hannelore; Sys, Gwen; Gijsels, Stefanie; Depypere, Herman T.; Tummers, Philippe; Ceelen, Wim; Craciun, Ligia; Demetter, Pieter; Raes, Olivier; Hendrix, An; Van der Eycken, Johan; De Wever, Olivier
Informations sur la publication:	Scientific reports, 14, 1, page (30188)
Statut de publication:	Publié, 2024-12-01
Sujet CREF:	Sciences bio-médicales et agricoles
Mots-clés:	Breast cancer
	Microtubule-stabilizing agent
	Ovarian cancer
	Paclitaxel
	Pelophen B
	Sarcoma
MeSH keywords:	Humans
	Microtubules -- metabolism -- drug effects
	Paclitaxel -- pharmacology
	Tubulin -- metabolism
	Cell Line, Tumor
	Antineoplastic Agents -- pharmacology -- chemistry
	Drug Resistance, Neoplasm -- drug effects
	Animals
	G2 Phase Cell Cycle Checkpoints -- drug effects
	Cell Survival -- drug effects
	Lactones -- pharmacology -- chemistry -- metabolism
	Tubulin Modulators -- pharmacology -- chemistry
Langue:	Anglais
Identificateurs:	urn:issn:2045-2322
	info:doi/10.1038/s41598-024-80672-z
	info:pii/10.1038/s41598-024-80672-z
	info:pmid/39633082
	PMC11618378