• Citer

Acute hepatitis induced by glatiramer acetate.

par Deltenre, Pierre ;Peny, Marie-Odile ;Dufour, André;El Nady, M;Henrion, Jean
Référence BMJ case reports, 2009
Publication Publié, 2009

Article révisé par les pairs

• Détails
• Contenu

Résumé :

Glatiramer acetate, a mixture of synthetic polypeptides able to prevent autoimmune encephalomyelitis in experimental models, is used as a treatment for patients with active relapsing-remitting multiple sclerosis. We report one case of glatiramer acetate induced hepatitis. Liver biopsy was consistent with a diagnosis of drug induced hepatitis and alanine aminotransferase returned to normal values after treatment discontinuation. The present case should serve as a warning that glatiramer acetate may cause acute liver disease.