Titre:
  • Genetic variants in PNPLA3 and TM6SF2 predispose to the development of hepatocellular carcinoma in individuals with alcohol-related cirrhosis.
Auteur:Stickel, Felix; Buch, Stephan; Nischalke, Hans Dieter; Weiss, Karl Heinz; Gotthardt, Daniel; Fischer, Janett; Rosendahl, Jonas; Marot, Astrid; Elamly, Mona; Casper, Markus; Lammert, Frank; McQuillin, Andrew; Zopf, Steffen; Spengler, Ulrich; Marhenke, Silke; Kirstein, Martha MM; Vogel, Arndt; Eyer, Florian; von Felden, Johann; Wege, Henning; Buch, Thorsten; Schafmayer, Clemens; Braun, Felix; Deltenre, Pierre; Berg, Thomas; Morgan, Marsha Y; Hampe, Jochen
Informations sur la publication:The American journal of gastroenterology, 113, 10, page (1475-1483)
Statut de publication:Publié, 2018-10-01
Sujet CREF:Sciences bio-médicales et agricoles
MeSH keywords:Acyltransferases -- genetics
Aged
Carcinoma, Hepatocellular -- genetics -- pathology
Case-Control Studies
Disease Progression
Europe
Female
Genetic Predisposition to Disease
Genotype
Humans
Lipase -- genetics
Liver -- pathology
Liver Cirrhosis, Alcoholic -- genetics -- pathology
Liver Neoplasms -- genetics -- pathology
Male
Membrane Proteins -- genetics
Middle Aged
Polymorphism, Single Nucleotide
Langue:Anglais
Identificateurs:urn:issn:0002-9270
info:doi/10.1038/s41395-018-0041-8
info:pmid/29535416